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Thiruvananthapuram, May 12:
A leading Indian scientist has urged the country’s medical community to update standard reference ranges for blood tests, arguing that current values-largely based on Western populations-may not accurately reflect the health profiles of Indians. The call was made by Professor Ullas Kolthur-Seetharam, Director of the Centre for DNA Fingerprinting and Diagnostics (BRIC-CDFD), Hyderabad, during his keynote lecture on National Technology Day 2025 at the Biotechnology Research and Innovation Council–Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB) in Thiruvananthapuram.
“While blood parameters are fundamental to diagnosing metabolic disorders like diabetes and cardiovascular disease, emerging research underscores that many standard reference ranges may need to be re-optimised for Indian populations,” Professor Kolthur-Seetharam said, according to an official statement from RGCB.
He highlighted that Indian laboratories typically use reference values derived from Western data, which may not account for the unique genetic, dietary, and environmental factors affecting Indian populations. “Genetic, dietary, and environmental differences can alter biomarkers, as can life-history trajectories,” he explained. “Cutting-edge research is uncovering how acute and chronic dietary changes influence health at the most fundamental level-through mitochondrial function and epigenetic regulation.”
Professor Kolthur-Seetharam, currently on deputation from the Tata Institute of Fundamental Research (TIFR), Mumbai, is renowned for his work on the interplay between mitochondrial function, epigenetics, and nutrition. He also established the Advanced Research Unit on Metabolism, Development & Ageing (ARUMDA) at TIFR, which addresses India’s growing challenges of malnutrition, non-communicable diseases, and ageing through interdisciplinary research.
Presiding over the event, Prof Chandrabhas Narayana, Director of BRIC-RGCB, underscored the importance of the National Technology Day 2025 theme: “Empowering Indian Youth for Global Leadership in Science & Innovation for Viksit Bharat.” He emphasized the institution’s commitment to fostering innovation, research, and entrepreneurship among young scientists and entrepreneurs, positioning India at the forefront of global scientific advancement.
Disclaimer:
This article is based on information reported by PTI and published by The Week on May 12, 2025. The statements and opinions expressed are those of the individuals quoted and do not necessarily reflect the official position of any government or health authority. For medical advice or interpretation of blood test results, please consult a qualified healthcare professional.
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