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Cancer is one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases in 2012 (1).
The number of new cases is expected to rise by about 70% over the next 2 decades.
Cancer is the second leading cause of death globally, and was responsible for 8.8 million deaths in 2015. Globally, nearly 1 in 6 deaths is due to cancer.
Approximately 70% of deaths from cancer occur in low- and middle-income countries.
Around one third of deaths from cancer are due to the 5 leading behavioral and dietary risks: high body mass index, low fruit and vegetable intake, lack of physical activity, tobacco use, and alcohol use.
Tobacco use is the most important risk factor for cancer and is responsible for approximately 22% of cancer deaths (2).
Cancer causing infections, such as hepatitis and human papilloma virus (HPV), are responsible for up to 25% of cancer cases in low- and middle-income countries (3).
Late-stage presentation and inaccessible diagnosis and treatment are common. In 2017, only 26% of low-income countries reported having pathology services generally available in the public sector. More than 90% of high-income countries reported treatment services are available compared to less than 30% of low-income countries.
The economic impact of cancer is significant and is increasing. The total annual economic cost of cancer in 2010 was estimated at approximately US$ 1.16 trillion (4).
Only 1 in 5 low- and middle-income countries have the necessary data to drive cancer policy (5).

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