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Key facts

  • In 2021, nearly half of the world’s population was at risk of malaria.
  • That year, there were an estimated 247 million cases of malaria worldwide.
  • The estimated number of malaria deaths stood at 619 000 in 2021.
  • The WHO African Region carries a disproportionately high share of the global malaria burden. In 2021, the Region was home to 95% of malaria cases and 96% of malaria deaths. Children under 5 accounted for about 80% of all malaria deaths in the Region.

The WHO Guidelines for malaria supersedes 2 previous WHO publications: the Guidelines for the Treatment of malariathird edition and the Guidelines for malaria vector control. Recommendations on malaria will continue to be reviewed and, where appropriate, updated based on the latest available evidence.

This version of the Guidelines includes revised information regarding the WHO recommendation for use of indoor residual spraying to prevent malaria and the conditional recommendation against the use of topical repellents to control malaria at the community level. It replaces the versions published on 16 February 2021, 13 July 2021, 18 February 2022, 31 March 2022, 3 June 2022, 25 November 2022 and 14 March 2023.

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Malaria Guidelines 2023

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