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TORONTO, ON – A new study has revealed a significant link between untreated infertility in women and an increased risk of developing systemic autoimmune rheumatic diseases (SARD) after childbirth. The research, conducted in Ontario, Canada, suggests that women with untreated infertility face a 25% higher risk of developing SARD within nine years post-delivery compared to women without infertility.
The population-based cohort study, analyzed a large dataset of women and found that the incidence rate of SARD was notably higher in women with untreated infertility. Specifically, it was 12.5 per 10,000 person-years in this group, compared to 9.3 per 10,000 person-years in women without infertility.
Crucially, this increased risk remained significant even after adjusting for adverse pregnancy outcomes, indicating that the association is not solely attributable to complications during pregnancy.
Interestingly, the study found no increased risk of SARD associated with either non-invasive or invasive fertility treatments. This suggests that addressing infertility through medical intervention may mitigate the risk. The link between untreated infertility and SARD was also observed in younger women (under 38) and those without pre-existing autoimmune conditions or endometriosis, reinforcing the study’s findings.
Researchers believe that potential mechanisms related to ovulatory, ovarian, and sexual dysfunction may play a role in this association. They emphasize the need for further research to understand these mechanisms fully.
The study authors also highlighted the importance of increasing awareness among healthcare providers regarding SARD symptoms and related gynecological issues in women with infertility. Early detection and treatment of SARD during the reproductive years could significantly improve patient outcomes.
“This research underscores the importance of addressing infertility and monitoring women with a history of untreated infertility for potential autoimmune conditions,” stated researchers involved in the study.
The findings call for further investigation into the underlying biological pathways connecting untreated infertility and SARD, aiming to develop targeted interventions and preventive strategies.
Disclaimer: This news article is based on information provided from a single study and should not be interpreted as definitive medical advice. Further research is needed to confirm these findings and understand the underlying mechanisms. Individuals with concerns about infertility or autoimmune diseases should consult with their healthcare provider for personalized advice and treatment.
