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A recent study led by the Baker Heart and Diabetes Institute offers new insights for individuals with a family history of early-onset heart disease, highlighting effective management strategies for those at intermediate risk.
Understanding the Study
The research, conducted in collaboration with the Menzies Institute for Medical Research and the Victorian Heart Institute, involved nearly 1,100 participants aged between 40 and 70. These individuals had a first-degree relative who developed coronary artery disease before the age of 60, or a second-degree relative before 50.
Of the participants, 450 were identified as being at intermediate risk. They were randomly assigned to receive either usual care or a combination of practitioner-led education informed by Coronary Artery Calcium Score (CACS) imaging and lifestyle interventions, including moderate-intensity statin therapy.
Key Findings
The study revealed that integrating CACS imaging—a CT scan that detects calcium deposits in the heart’s arteries—with targeted education significantly improved patient engagement in preventive measures. This approach led to higher adherence rates to statin therapy, with participants showing improved lipid profiles and a slower progression of arterial plaque buildup compared to usual care.
Professor Tom Marwick, the lead researcher and a cardiologist, emphasized that utilizing the Coronary Calcium Score is highly beneficial in managing individuals with inherited coronary artery disease. He noted that this method enhances patient involvement in prevention strategies, addressing the typically low adherence rates observed in standard practices.
Implications for At-Risk Individuals
For those with a family history of early heart disease, this study offers reassurance and practical guidance. The findings suggest that personalized education combined with advanced imaging techniques and lifestyle modifications can effectively reduce heart disease risk.
Disclaimer: This article is based on information from the study “Study provides greater reassurance for people at risk of inherited heart disease” as reported by Medical Xpress. The content is intended for informational purposes only and should not be considered medical advice. Consult with a healthcare professional for personalized medical guidance.
