Rutgers University researchers have innovated a remarkably precise technique to coat medical products with biologically active substances. This breakthrough holds the potential to open the doors to a new era of transdermal medication, encompassing methods like needle-free vaccinations.
In an article published in Nature Communications, the scientists detail a novel approach to electrospray deposition, an industrial process used for spray-coating. Essentially, the team at Rutgers has formulated a method to exert finer control over both the specific region within the spray zone and the electrical properties of the microscopic particles being deposited. This heightened manipulation of these two factors enhances the likelihood of more accurately directing the spray towards its minuscule target.
The process of electrospray deposition involves the application of high voltage to a flowing liquid, often containing biopharmaceuticals, causing it to morph into fine particles. As these droplets traverse to a designated area, they undergo evaporation, leaving behind a solid precipitate derived from the original solution.