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Los Angeles, CA – A new study reveals that listening to music from one’s past can trigger a powerful neurological response, activating brain regions linked to memory and reward. Researchers have discovered that nostalgic music not only evokes vivid memories but also engages key brain networks, potentially offering a valuable tool for individuals with memory impairments like Alzheimer’s disease.
The study, led by Assal Habibi of the Brain and Creativity Institute (BCI) at the USC Dornsife College of Letters, Arts and Sciences, and published in the journal Human Brain Mapping, utilized functional MRI (fMRI) to monitor participants’ brain activity as they listened to personally significant songs. The findings demonstrated that nostalgic music activates both the brain’s default mode network, associated with self-reflection and memory recall, and its reward circuitry, which processes pleasure and motivation.
“Music is deeply intertwined with our sense of identity and personal history,” stated Habibi, associate professor of psychology and neurology. “What we’re seeing is that nostalgic songs don’t just bring back memories—they activate the brain in ways that could support emotional well-being and cognitive function, especially in individuals living with memory impairments.”
The research team, including lead author Sarah Hennessy, currently a postdoctoral scholar at the University of Arizona, along with Jonas Kaplan and Talia Ginsberg of USC Dornsife, and Petr Janata of the University of California, Davis, observed a unique neural signature when participants listened to songs tied to meaningful life events. This neural signature may explain music’s ability to trigger strong, autobiographical memories.
The findings suggest a promising, non-pharmacological approach to improving the quality of life for individuals experiencing memory loss. By leveraging personalized playlists, caregivers and therapists may be able to help patients reconnect with their past and enhance their emotional well-being.
“This research points to the power of music as a tool for memory support,” said Hennessy. “We hope these findings inspire further exploration into how music can be used to improve cognitive function and emotional health.”
The study provides scientific insight into the profound connection between music, memory, and emotion, highlighting its potential to positively impact individuals with memory-related conditions.
More information: Sarah Hennessy et al, Music‐Evoked Nostalgia Activates Default Mode and Reward Networks Across the Lifespan, Human Brain Mapping (2025). DOI: 10.1002/hbm.70181
Journal information: Human Brain Mapping
Disclaimer: This news article is based on the provided information and should not be taken as medical advice. The findings of this study are promising, but further research is needed to fully understand the clinical applications of music therapy for memory-related conditions. Individuals with memory impairments should consult with healthcare professionals for appropriate diagnosis and treatment.
