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The Omicron variant of SARS-CoV-2 escapes immunity generated by vaccines and previous infections yet seems to have some unexpected advantages over the other variants we have experienced so far. Firstly, and most importantly, strong evidence is emerging that the disease induced by infection with Omicron is considerably milder at the population level.  Secondly, infection with Omicron has been shown to trigger cross-protective immunity to the more pathogenic Delta variant, which together with Omicron’s advantage in transmissibility, may set Delta on the path to extinction.

 

Further, read at nature reviews immunology at https://www.nature.com/articles/s41577-022-00678-4#Fig1

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