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In a groundbreaking study led by Yale researchers, methadone treatment has been shown to significantly enhance HIV care for individuals transitioning from prison to the community. The study, published in the International Journal of Drug Policy, highlights the critical role methadone plays in improving health outcomes for people with both HIV and opioid use disorder following their release.

Formerly incarcerated individuals often struggle with employment, housing, and healthcare access upon reentry into society. These challenges are even more severe for those living with HIV or opioid use disorder, conditions that increase the risk of medical complications and mortality.

“We knew that there is a synergistic effect between addiction and HIV,” said Dr. Frederick Altice, professor of medicine at Yale School of Medicine and of epidemiology at Yale School of Public Health. “We hypothesized that if we could directly address that synergy by optimizing the treatment for the substance-use disorder, we could have an impact on HIV treatment and prevention.”

Study Findings

The study focused on 296 incarcerated individuals with HIV and opioid use disorder from Malaysia’s largest prison. Participants were randomly assigned to receive pre-release methadone treatment, a risk-reduction behavioral intervention, neither, or both. Those prescribed methadone were significantly more likely to engage in HIV care within 30 days of release, with engagement rates increasing more than 2.5 times within a year.

Dr. Allison Mobley, the study’s first author, emphasized that these findings go beyond treating opioid use disorder, which is already well-documented. “This study quantitatively demonstrates how methadone treatment can enhance HIV care and outcomes,” she stated.

A Call for Policy Change

Beyond the individual health benefits, implementing methadone treatment in prisons could help break the cycle of recidivism and health disparities among marginalized populations. “It would be a significant step toward dismantling the cycle of recidivism and health disparity that affects these individuals,” said Mobley.

Dr. Altice stressed that the research serves as a call to action for policymakers and prison administrators worldwide. “Integrating methadone treatment into prison healthcare systems is a critical step toward achieving global HIV targets and improving public health outcomes.”

The study was made possible through a longstanding collaboration with researchers in Malaysia. Other Yale authors include Dr. Sheela Shenoi, Dr. Daniel Bromberg, and Dr. Ahsan Ahmad.

Conclusion

With mounting evidence supporting the benefits of methadone treatment for formerly incarcerated individuals with HIV and opioid use disorder, experts urge governments and prison systems to implement these programs as a standard practice. Doing so could not only improve individual health outcomes but also reduce HIV transmission and bolster public health.

Disclaimer: This article is based on a research study and is intended for informational purposes only. It does not constitute medical advice. Individuals seeking treatment should consult with healthcare professionals.

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