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New Delhi: India has achieved a significant milestone in medical science by conducting the first human clinical trial of gene therapy for haemophilia A, announced Union Science & Technology Minister Dr. Jitendra Singh. This breakthrough trial took place at Christian Medical College (CMC) Vellore, underlining India’s prowess in cutting-edge medical research and innovation.
Dr. Jitendra Singh made this announcement while addressing the “National Science Day 2024” programme at Vigyan Bhawan, New Delhi, emphasizing India’s commitment to advancing scientific research and technology.
The gene therapy trial for haemophilia A, also known as FVIII deficiency, marks a significant stride in medical science. The trial, supported by the Department of Biotechnology and the Centre for Stem Cell Research, in collaboration with Emory University, USA, witnessed the deployment of a novel technology using a lentiviral vector. This vector facilitated the expression of a FVIII transgene in the patient’s own haematopoietic stem cells, which subsequently expressed FVIII from specific differentiated blood cells.
Expressing optimism about the future prospects of this breakthrough, Dr. Jitendra Singh highlighted the potential commencement of vector manufacturing in India, paving the way for further clinical trials. He emphasized the pivotal role of this achievement in augmenting India’s healthcare capabilities and providing innovative solutions to critical medical conditions.
Reflecting on the significance of the National Science Day, commemorating the discovery of the “Raman Effect” by Nobel Laureate Sir CV Raman, Dr. Jitendra Singh underscored India’s unwavering commitment to scientific advancement. He reiterated Prime Minister Narendra Modi’s vision of harnessing the power of science and technology to propel India towards progress and development.
Dr. Jitendra Singh also shed light on India’s remarkable achievements in the field of science and technology under the leadership of Prime Minister Modi. He highlighted India’s exponential growth in the bio-economy, which has surged from $10 billion in 2014 to over $130 billion in 2024. Furthermore, he emphasized India’s burgeoning startup ecosystem, advanced technologies, and transformative initiatives such as the Aroma Mission and Purple Revolution in agriculture.
Acknowledging the increasing role of women scientists, Dr. Jitendra Singh commended the empowerment of the women scientific community under PM Modi’s leadership, citing numerous women-led initiatives and programs in scientific institutions and space missions.
As the event concluded, Dr. Jitendra Singh reiterated India’s commitment to scientific excellence and innovation, underscoring the nation’s resolve to address healthcare challenges through pioneering research and technological advancements.
