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The Indian Council of Medical Research–National Institute of Epidemiology (ICMR-NIE) has initiated a comprehensive study to determine the prevalence of Kyasanur Forest Disease (KFD), commonly known as “monkey fever,” across the Western Ghats. This effort spans five states—Karnataka, Tamil Nadu, Kerala, Maharashtra, and Goa—where the disease has been a persistent public health concern.
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: The study aims to assess the sero-prevalence of KFD in both endemic and non-endemic districts of the Western Ghats. Sero-prevalence studies help identify the true burden of infection within a population over time.
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: Findings will guide state governments in identifying high-risk areas for focused vaccination efforts, especially as new vaccine trials are on the horizon.
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: KFD is characterized by sudden high-grade fever, extreme fatigue, nausea, vomiting, diarrhea, and, in some cases, neurological and hemorrhagic complications.
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: The disease is transmitted to humans through the bite of infected ticks.
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: Annually, KFD leads to 250–300 deaths in the region, highlighting the need for effective intervention.
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: An earlier vaccine developed by a Bengaluru-based firm was discontinued due to ineffectiveness. Currently, ICMR is developing a new two-dose vaccine, with the second dose administered after the first. Preclinical trials are underway, and clinical trials will commence soon to determine the vaccine’s efficacy.
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: Karnataka, which reported over 100 cases and one death this year, has actively requested ICMR’s support in vaccine development to curb fatalities in forested areas.
Dr. Manoj V Murhekar, Director of ICMR-NIE, emphasized the importance of the study for targeted vaccination and reducing the disease burden. A senior health official from Karnataka echoed the urgency, noting the significant threat KFD poses to communities in the Western Ghats.
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This article is based on publicly available information as of July 7, 2025. For the latest updates on Kyasanur Forest Disease and vaccination efforts, please consult official health sources or your local health department. The information provided here does not constitute medical advice.
