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NEW DELHI, April 26, 2025 – A recent study from Denmark has ignited discussion about a potential link between the use of hormonal intrauterine devices (IUDs) and an increased risk of breast cancer, particularly with long-term use. However, researchers stress that while the relative risk may increase, the absolute increase in cases remains small, highlighting the need for careful interpretation.
The study analysed data spanning two decades, comparing nearly 80,000 individuals who started using hormonal IUDs with a similar-sized group who did not use them. Initial observations seemed counterintuitive, suggesting hormonal IUD users might have a lower risk, with 720 breast cancer cases reported compared to almost 900 in the non-user group.
However, the researchers noted the study’s observational nature, acknowledging potential underlying differences between the women who chose IUDs and those who didn’t. After statistically adjusting for factors such as education level and medical history to create a more comparable baseline, the analysis shifted. The adjusted data indicated a higher breast cancer risk associated with hormonal IUD use.
This increased risk appeared to correlate with the duration of use. The study reported a relative risk increase of 30% after five years of hormonal IUD use, rising to an 80% relative increase for those using the devices for 10 to 15 years.
Despite these significant relative risk figures, the study emphasizes the importance of considering the absolute risk. In real terms, the researchers estimated that five years of hormonal IUD use could lead to approximately 14 additional breast cancer cases for every 10,000 women using the device. This absolute number is substantially lower than the relative risk percentages might suggest.
Experts caution against drawing definitive conclusions solely from this observational study. They point out that other research on the topic has indicated lower risks associated with hormonal IUDs. Furthermore, the overall health benefits of hormonal IUDs as an effective contraceptive method must be weighed against any potential risks. Women are advised to discuss their individual circumstances and contraceptive options thoroughly with their healthcare providers.
Disclaimer: This news article is based on information from a recent study and is intended for informational purposes only. It does not constitute medical advice. Individuals should consult with a qualified healthcare professional for any health concerns or before making any decisions related to1 their health or treatment, including contraceptive choices.
