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March 2, 2025 – A comprehensive global study on ovarian cancer has uncovered significant regional variations in incidence and changing trends in histological subtypes. The research highlights the need for targeted prevention and treatment strategies tailored to specific populations.
The study, published in eClinicalMedicine, analyzed data from the 2024 Cancer Incidence in Five Continents (CI5) volume XII and CI5plus databases, examining incidence patterns from 2013 to 2017 and temporal trends over 30 years across numerous countries.
Key findings of the study include:
- Regional Variations:
- Eastern and Central Europe and regions with very high Human Development Indices (HDIs) reported the highest age-standardized ovarian cancer incidence rates.
- Africa, Asia, and regions with medium HDIs showed the lowest rates.
- Temporal Trends:
- Ovarian cancer incidence rates have decreased over time in Europe, America, and Oceania.
- Incidence rates have increased in Asian countries, including Japan and South Korea.
- Histological Subtypes:
- Serous carcinomas were the most prevalent subtype globally, particularly in Europe.
- Mucinous carcinomas were more common in Asia.
- Serous carcinomas and germ cell tumors showed an upward trend in prevalence, while mucinous carcinomas and adenocarcinomas demonstrated declining rates.
- Age-Specific Incidence:
- Incidence rates consistently increased with age, peaking between 70 and 84 years for most subtypes.
- Sex cord-stromal tumors and germ cell tumors remained consistently low across all age groups.
These findings underscore the importance of understanding the complex factors influencing ovarian cancer incidence and subtype distribution. The observed regional and temporal variations suggest that environmental, genetic, and lifestyle factors may play significant roles.
Disclaimer: This news article is based on information available at the time of publication and reflects the findings of a specific study. Cancer research is ongoing, and further studies may provide additional insights or modify current understandings. This article is for informational purposes only and does not constitute medical advice. Individuals with concerns about ovarian cancer or their health should consult with a qualified healthcare professional for diagnosis, treatment, and personalized guidance.
