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A recent study published in Frontiers in Endocrinology has revealed a concerning trend: the global burden of diabetic nephropathy, or kidney disease caused by diabetes, has significantly increased between 1990 and 2021, and is projected to continue its upward trajectory until 2050.
Researchers, led by Xiao Ma from The Third People’s Hospital of Chengdu in China, analyzed data from the Global Burden of Disease Study to assess the worldwide impact of chronic kidney disease (CKD) stemming from both type 1 and type 2 diabetes. Their analysis, which spanned over three decades, highlighted a worrying surge in cases.
The study revealed significant variations in the burden of diabetic nephropathy across different countries and regions, categorized by their sociodemographic index. The researchers also observed that different age groups and metabolic factors played varying roles in contributing to the disease’s burden. Furthermore, a positive correlation was found between the impact of metabolic factors and both the number of deaths and mortality rates with advancing age.
“The burden of diabetic nephropathy and its estimated annual percentage changes (EAPCs) varied significantly across different sociodemographic index subgroups of countries and regions worldwide,” the researchers stated.
Notably, the study found that different metabolic factors have distinct effects on mortality rates associated with CKD caused by type 1 and type 2 diabetes. Using an ARIMA (Autoregressive Integrated Moving Average) model, the researchers projected a continued rise in the global burden of diabetic nephropathy from 2022 to 2050, assuming no significant interventions are implemented.
“In the absence of interventions, the global burden of diabetic nephropathy is projected to continue to rise annually from 2022 to 2050, placing even greater stress on the global health system in the future,” the authors concluded.
This study underscores the urgent need for effective interventions and strategies to mitigate the growing burden of diabetic nephropathy worldwide.
Disclaimer: This news article is based on information provided in the referenced research study. Medical information is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in this article. The projections made within the study are based on statistical models and may not perfectly predict future outcomes.
