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 March 23, 2024

A new study published in JAMA Network Open: Cardiology reveals that people with highly variable body mass index (BMI) measurements, characterized by repeated fluctuations in weight, may face increased risks of serious cardiovascular issues. The research, drawing on data from the Million Veteran Program and the UK Biobank, underscores the importance of weight stability for heart health.

The study, conducted by a team of researchers, analyzed data spanning from 2011 to 2018 and included participants from both programs. Over an average follow-up period of nearly 4 years, researchers observed a clear association between highly variable BMI and adverse cardiovascular events, independent of common risk factors and genetic predispositions.

Dr. Hosam Hmoud, a cardiology fellow at Northwell Lenox Hill Hospital, highlights the significance of BMI fluctuations in cardiovascular health. “Central obesity, reflected in high BMI, is a known risk factor for atherosclerotic cardiovascular disease, diabetes, and kidney disease,” he explains. Elevated BMI levels are often accompanied by increased adipose tissue, releasing pro-inflammatory chemicals that contribute to various chronic conditions.

BMI, a measure of body fat based on height and weight, serves as a crucial marker for overall health. However, the study reveals that fluctuations in BMI can pose additional strain on the heart and other organs, potentially exacerbating the risk of cardiovascular disease.

“The study highlights the importance of achieving a healthy body weight through sustainable lifestyle changes,” says Brooke Aggarwal, an assistant professor at Columbia University Vagelos College of Physicians and Surgeons. Sustainable weight management strategies, including regular exercise and a balanced diet, are essential for maintaining optimal BMI levels and reducing the risk of cardiovascular issues.

The findings underscore the need for comprehensive support for individuals striving to achieve and maintain a healthy weight. “Conventional diets that focus on severe calorie restriction often fail to yield sustained weight reduction and health benefits,” notes Aggarwal. Instead, she advocates for intuitive and mindful eating approaches, emphasizing gradual weight loss and long-term lifestyle changes.

As researchers continue to investigate the complex relationship between BMI fluctuations and cardiovascular health, the study underscores the importance of prioritizing heart health through proactive measures such as regular exercise, healthy eating habits, and weight management strategies tailored to individual needs.

Maintaining a healthy BMI is essential for overall well-being, and individuals are encouraged to consult with healthcare professionals for personalized guidance and support in achieving their health goals.

The study was conducted with support from the Million Veteran Program and the UK Biobank and contributes to ongoing efforts to enhance cardiovascular health outcomes.

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