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A recent study published in Nature Aging suggests that consuming one gram of omega-3 fatty acids daily may help slow down biological aging in humans. The findings are based on an analysis of data from a clinical trial involving over 700 older adults over a three-year period.
Study Overview
Previous research has indicated that caloric restriction may decelerate aging in humans. Other studies, including animal research and small-scale human trials, have explored the potential anti-aging benefits of vitamin D and omega-3. However, the effectiveness of these interventions in a larger human population has remained uncertain.
To investigate further, researchers Heike Bischoff-Ferrari, Steve Horvath, and colleagues conducted a clinical trial involving 777 Swiss participants aged 70 and older. They employed molecular biology tools known as epigenetic clocks to assess the impact of different interventions on biological aging rates.
Key Findings
During the trial, participants followed one or more of the following interventions:
- Consuming 2,000 International Units (IU) of vitamin D per day
- Taking 1 gram of omega-3 fatty acids per day
- Engaging in a 30-minute home exercise program three times per week
The analysis of blood samples revealed that omega-3 intake alone moderately slowed biological aging, reducing the rate by up to four months according to several epigenetic clocks. These effects were consistent across sex, age, and body mass index. Furthermore, a combination of omega-3, vitamin D, and exercise demonstrated an even stronger impact on slowing biological aging.
Additional Benefits
Beyond aging-related effects, the study found that combining all three interventions significantly reduced cancer risk and helped prevent frailty over the three-year span. Researchers suggest that each intervention operates through distinct but interconnected biological pathways, reinforcing one another when used together.
Study Limitations
The authors acknowledge that the study has certain limitations. There is no universally accepted measure of biological aging, and the study relied on the most-validated tests available. Additionally, the sample consisted solely of Swiss participants, which may not be representative of the broader global population of older adults.
Conclusion
While these findings are promising, further research is needed to confirm whether omega-3, vitamin D, and exercise have the same effects across different populations. Those considering omega-3 supplementation for anti-aging benefits should consult healthcare professionals before making any changes to their dietary or lifestyle habits.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider before making any changes to your diet, exercise, or supplement routine.
