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August 18, 2025 — New research has revealed that a COVID-19 infection may dramatically accelerate the aging of blood vessels, particularly in women, resulting in vascular changes equivalent to around five years of natural aging. The findings, detailed in a publication from the European research community, add to the growing body of evidence linking COVID-19 to long-term cardiovascular health risks.
Key Study Findings
According to the research, women who experienced COVID-19 infections showed the greatest levels of blood vessel aging. The process involves increased blood vessel stiffness, which is a strong predictor of future heart disease and stroke. The study highlights that, following COVID infection, individuals—especially women—could face heightened risks of developing cardiovascular complications for years after their recovery.
This new data builds on previous discoveries that SARS-CoV-2, the virus causing COVID-19, targets cells rich in ACE2 receptors, abundant in both lungs and blood vessels. When the virus invades these cells, it provokes a strong inflammatory response, leading to increased blood vessel stiffness and accelerated vascular aging. Several studies have also associated COVID’s impact on the lining of blood vessels (endothelium) with increased risk for heart attacks and strokes—sometimes years after the initial infection.
Long-Term Vascular Risk Highlighted
Vascular experts explain that these changes go beyond short-term recovery. In what is now referred to as vascular long-COVID, lingering damage to the arteries and blood vessels can result from persistent inflammation and immune dysregulation. Researchers recommend increased cardiovascular monitoring, particularly for women with a history of COVID-19, and urge healthcare professionals to pay close attention to new or worsening cardiovascular symptoms post-infection.
Implications for Public Health
As the effects of COVID-19 continue to unfold, these findings underscore the importance of long-term follow-up and management for people recovering from the virus. Preventing future complications may involve early screening, lifestyle modification, and, when appropriate, medical interventions to address blood pressure, cholesterol, and other risk factors aggravated by vascular aging.
“Covid infection may accelerate vascular aging, particularly in women, increasing blood vessel stiffness and raising cardiovascular risk even years after the infection has cleared.”x
Disclaimer
This news article is provided for informational purposes only and should not be considered a substitute for professional medical advice. Individuals concerned about their cardiovascular health or recovering from COVID-19 are encouraged to consult a qualified healthcare provider.
Reference
Medical Xpress. “COVID infection ages blood vessels, especially in women.” (August 17, 2025).
