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Fairfax, Virginia — A recent study has revealed a potential link between long-distance running such as marathons and an increased risk of developing colon cancer precursors. The research, led by oncologist Dr. So Cannon from Inova Schar Cancer Center, involved 100 marathon and ultramarathon runners aged 35 to 50 undergoing colonoscopy screenings. The results were surprising: nearly half of these athletes had colon polyps, and 15% had advanced adenomas, which are precancerous lesions likely to evolve into colon cancer. This rate is significantly higher than the 4.5% to 6% typically observed in the general population of adults in their late 40s.
Presented at an American Society of Clinical Oncology conference but not yet published in a peer-reviewed medical journal, the study emerges amid growing alarm about rising cases of colorectal cancer among adults under 50. Traditionally, this younger group has been considered at lower risk, but recent trends have prompted the US Preventive Services Task Force to lower the recommended age for initial colonoscopy screening from 50 to 45 for average-risk individuals.
While physical inactivity and obesity have often been blamed for the increase in early-onset colorectal cancers, Dr. Cannon’s study suggests that extreme endurance running may paradoxically raise cancer risk in this group. However, experts caution against interpreting these findings as a reason to avoid exercise, which remains crucial for overall health.
“Exercise, in general, combats many health problems, but our findings indicate that excessive endurance running may increase colorectal cancer risk in some individuals,” Dr. Cannon said. The study’s provocative findings highlight the need for further research to understand the complex factors behind the rising incidence of colon cancer in younger adults.
Physicians emphasize that most young colon cancer patients are not marathon runners and that this line of investigation is new. Nonetheless, monitoring and early screening for colorectal cancer remain vital preventive measures, especially as incidence rises in younger populations.
Disclaimer: This article is for informational purposes only and does not substitute professional medical advice. Individuals concerned about colorectal cancer risk or screening should consult healthcare professionals.
Reference: Economic Times. Colon Cancer linked to marathons, half-marathons, long-distance running? Read shocking details. August 2025. Available at:
