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In a promising development for managing type 2 diabetes, a new study published in The Lancet Diabetes & Endocrinology has demonstrated that a behavioral intervention designed to support weight loss can lead to remission of the condition. The research, led by Dr. Jonathan Valabhji from NHS England, highlights the potential for a structured diet intervention to achieve significant health improvements in individuals with type 2 diabetes.
The study evaluated the NHS Type 2 Diabetes Path to Remission program, a comprehensive 12-month initiative that includes a three-month phase of total diet replacement. Participants in this phase consumed nutritionally formulated products, including soups, shakes, and bars, while maintaining a daily calorie intake of 800 to 900 kcal.
Out of the 1,740 participants who began the program before January 2022, 55% completed the intervention by the end of the 12-month period, with their weight data recorded. The results revealed a mean weight loss of 8.3% (9.4 kg) for those who started the program, and a more significant loss of 9.3% (10.3 kg) for those who completed it.
Notably, the study found that 27% of a subgroup of 710 participants who had two hemoglobin A1c (HbA1c) measurements recorded achieved remission, with an average weight loss of 13.4% (14.8 kg). Among the 450 participants who completed the program and also had two HbA1c measurements recorded, 32% achieved remission, with an average weight loss of 14.4% (15.9 kg).
Dr. Valabhji and colleagues concluded that remission of type 2 diabetes is attainable outside of controlled research environments through large-scale programs. However, they noted that the remission rates observed in this real-world setting were slightly lower compared to those reported in randomized controlled trials.
The findings offer hope for individuals struggling with type 2 diabetes and highlight the effectiveness of structured weight loss programs in achieving disease remission. The study underscores the importance of accessible, scalable interventions for managing chronic conditions.
For further reading, the study is available here.
Journal information: The Lancet Diabetes & Endocrinology
