Osaka, Japan – A recent international study has shed light on the diverse approaches to Helicobacter pylori (H. pylori) treatment across the Asia-Pacific region, a critical area given the bacteria’s strong link to gastric cancer. The research, led by Dr. Koji Otani and Professor Yasuhiro Fujiwara of Osaka Metropolitan University Graduate School of Medicine, highlights both progress and challenges in combating this significant health issue.
H. pylori, a bacterium responsible for approximately 90% of gastric cancer cases, poses a particularly high risk in the Asia-Pacific region. While preemptive eradication of the bacteria can reduce gastric cancer incidence by 30-40%, the growing problem of antimicrobial drug resistance complicates treatment. Furthermore, the effectiveness and importance of secondary prevention, such as endoscopic examinations for early detection, vary across the region.
To understand the current treatment landscape, the research team conducted an online survey of clinicians throughout the Asia-Pacific. The survey examined diagnostic methods, antibacterial drug dosages, treatment durations, and the perceived importance of secondary prevention. The results, published in the Journal of Gastroenterology and Hepatology, indicate a growing consensus among practitioners regarding the importance of both primary and secondary prevention against H. pylori.
“At present, differences in the incidence of antimicrobial resistance and gastric cancer between regions, medical resources, and policies are affecting the formation of uniform standards for gastric cancer prevention,” explained Dr. Otani. “In the future, it will be important to establish treatment guidelines for H. pylori infections that are appropriate for each region, taking into consideration the actual situation of antimicrobial resistance and gastric cancer in each Asian country.”
The study underscores the need for tailored strategies to address the unique challenges faced by each country in the region. The researchers hope their findings will contribute to the development of more effective and region-specific guidelines for H. pylori management and gastric cancer prevention.
More information: Koji Otani et al, Asia‐Pacific Survey on the Management of Helicobacter pylori Infection, Journal of Gastroenterology and Hepatology (2024). DOI: 10.1111/jgh.16862
Disclaimer: This news article is based on information provided in the referenced study. It is intended for informational purposes only and should not be construed as medical advice. Individuals with concerns about H. pylori or gastric cancer should consult with a qualified healthcare professional for diagnosis and treatment. The information presented here reflects the findings of the study and may not represent the views or recommendations of all medical professionals or organizations. Treatment recommendations and effectiveness can vary based on individual circumstances and local healthcare guidelines.