March 6, 2025 – A groundbreaking study has confirmed that bacterial vaginosis (BV), a condition affecting nearly one in three women worldwide and linked to infertility, premature births, and newborn deaths, is in fact a sexually transmitted infection (STI). This revelation paves the way for a significant shift in how the condition is treated.
Researchers from Monash University and Alfred Health at the Melbourne Sexual Health Center have published their findings in the New England Journal of Medicine, emphasizing the need to treat both sexual partners simultaneously to reduce the high recurrence rates of BV.
A Shift in Understanding and Treatment
Traditionally, BV has been treated as an imbalance in the vaginal microbiome, leading to more than 50% of women experiencing a recurrence within three months of treatment. However, researchers Professor Catriona Bradshaw and Dr. Lenka Vodstrcil argue that this approach fails to address the underlying issue—reinfection from male partners.
Their study involved 164 couples in monogamous relationships. Women received the standard week-long oral antibiotic treatment, while male partners were randomly assigned to receive either a combination of oral and topical antibiotic treatments or no treatment at all. The results were striking: BV recurrence was reduced by half when both partners were treated.
The trial was halted early due to the overwhelming success of partner treatment, indicating a significant breakthrough in BV management.
The Missing Link: Male Partners
Dr. Vodstrcil highlighted that BV shares risk factors with other STIs, such as unprotected sex and changes in sexual partners. While previous research suggested men could harbor BV-associated bacteria, past treatment trials failed to improve cure rates for female partners, leading to skepticism about sexual transmission.
Professor Bradshaw explained that earlier studies lacked comprehensive treatment methods. “Our trial used a combination of oral and topical antibiotics to clear BV-causing bacteria from men, particularly from the penile skin, which was a missing factor in previous research.”
A Call for Change in Clinical Practice
The study’s findings have already prompted the Melbourne Sexual Health Center to update its clinical guidelines to include partner treatment. Additionally, a new website has been launched to provide healthcare professionals and consumers with resources on accessing and prescribing partner treatment.
“This intervention is relatively affordable and short-term, yet it has the potential to improve BV cure rates, prevent recurrence, and reduce associated complications,” Professor Bradshaw stated.
While national and international treatment guidelines may take time to adapt, the research team is committed to ensuring that accurate and accessible information is available to both the medical community and the public.
Disclaimer:
This article is based on recent scientific research and aims to inform readers about potential developments in BV treatment. Individuals experiencing symptoms or concerns about bacterial vaginosis should consult a qualified healthcare professional for diagnosis and appropriate medical advice.