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March 2, 2025 – A long-term study conducted by Danish researchers has revealed a significantly increased risk of cardiovascular disease among male users of anabolic androgenic steroids (AAS). The research highlights the severe and persistent heart-related health risks associated with AAS use.
Anabolic androgenic steroids, synthetic derivatives of testosterone, are used to enhance muscle mass and strength. While prohibited in competitive sports, their use for body enhancement and recreational fitness remains prevalent.
The study, published in Circulation, examined 1,189 men sanctioned for AAS use in Danish fitness centers between 2006 and 2018. These participants were compared with 59,450 male controls from the general Danish population. Researchers assessed the incidence of various cardiovascular events, including acute myocardial infarction, percutaneous coronary intervention, venous thromboembolism, ischemic stroke, arrhythmia, cardiomyopathy, heart failure, and cardiac arrest.
It is important to note that the study did not specify whether AAS users continued or ceased use after being sanctioned, nor did it specify dosage or AAS type. However, the AAS user group showed significantly higher incidences of cardiovascular outcomes over an average follow-up of 11 years.
Key findings include:
- A threefold increased risk of acute myocardial infarction (HR 3.00) and percutaneous coronary intervention or coronary artery bypass graft (HR 2.95).
- A significantly higher risk of venous thromboembolism (HR 2.42).
- Arrhythmias occurring at 2.3 times the rate of the general population (HR 2.26).
- A 3.6-fold increased risk of heart failure (HR 3.63).
- A nearly ninefold increased risk of cardiomyopathy (HR 8.90).
Researchers concluded that AAS use is significantly associated with an elevated risk of major cardiovascular diseases, with these risks persisting over long-term follow-up.
“These findings underscore the serious and lasting impact of AAS use on cardiovascular health,” the researchers stated.
Disclaimer: This news article is based on information available at the time of publication and reflects the findings of a specific study. Epidemiological studies can identify associations but cannot establish cause-and-effect relationships. The study had limitations, such as not specifying AAS dosage or usage duration after the sanction. This article is for informational purposes only and does not constitute medical advice. Individuals with concerns about AAS use or cardiovascular health should consult with a qualified healthcare professional. The information regarding the study is based on information provided by the researchers and the publication.
