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New Delhi, Feb 26 (IANS) – Gastric bacteria leaking through the stomach lining play a significant role in the onset of stomach cancer, a disease with limited treatment options and poor survival rates, according to a new study.
The research, led by scientists from the University of Birmingham, has identified a crucial interaction between Helicobacter pylori (H. pylori) and non-H. pylori bacteria in the pre-cancerous stage of gastric cancer.
The study’s findings, published in the journal Helicobacter, could open new avenues for the prevention and treatment of the disease.
“We are excited about the potential of this observation to lead to new research in preventing stomach cancer. It is possible that a simple antibiotic treatment could target these bacteria. However, much more work remains to be done,” said Dr. Amanda Rossiter-Pearson, one of the lead researchers from the University of Birmingham.
Dr. Rossiter-Pearson emphasized the importance of identifying these bacteria and understanding how their presence in the pre-cancerous condition impacts a patient’s risk of developing stomach cancer.
Gastric Cancer and Bacterial Interaction
Gastric cancer is the fourth leading cause of cancer-related deaths worldwide. While H. pylori infection is known to be the primary risk factor, it remains unclear why only 1% of those infected develop stomach cancer.
To explore this further, the researchers utilized advanced imaging technology to analyze bacterial localization. The findings revealed that while H. pylori exclusively colonizes gastric glands, non-H. pylori bacteria tend to leak through the stomach lining in the pre-cancerous condition known as gastric intestinal metaplasia.
These results suggest that bacterial leakage into deeper gastric tissues may be a previously overlooked factor in cancer progression.
The Need for Early Detection and Alternative Treatments
Early detection of H. pylori can allow for eradication with antibiotics, significantly reducing the risk of gastric cancer. However, once pre-cancerous changes occur, antibiotic treatments against H. pylori become ineffective, highlighting the urgent need for alternative therapies.
The study provides new insights into the role of bacterial interactions in gastric cancer progression and could lead to future treatments that target both H. pylori and other gastric bacteria.
Disclaimer:
This article is for informational purposes only and should not be considered medical advice. Readers are encouraged to consult with healthcare professionals for any concerns regarding stomach cancer and its treatment.
