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Chicago, USA: A new study by the University of Chicago Medicine challenges long-held beliefs about the relationship between alcohol use disorder (AUD) and depression. Contrary to popular notions that people with depression drink primarily for self-medication, the research reveals that individuals with both AUD and depression experience similar levels of stimulation and pleasure from alcohol consumption as those without depression.

The study, published in the American Journal of Psychiatry, analyzed data from 232 participants aged 21 to 35, a demographic known for high levels of alcohol consumption. Half of the participants met the criteria for AUD in the past year, with an even distribution between those with and without a history of major depressive disorder.

Challenging Existing Theories

Lead researcher Andrea King, PhD, Professor of Psychiatry and Behavioral Neuroscience, emphasized the study’s findings: “We have this folklore that people drink excessively when they’re feeling depressed and that it’s really about self-medicating.” However, the study suggests that the pleasurable and rewarding effects of alcohol remain high among individuals with AUD, irrespective of their depression status.

Using smartphone-based real-time reporting, researchers found that alcohol consumption led to acute and sustained positive effects, similar across participants. While alcohol did reduce negative emotions, this effect was minimal and not directly related to depression or AUD status.

Implications for Treatment

The findings raise questions about existing treatment strategies for AUD, which often focus on alcohol’s role in stress reduction and self-medication. Instead, the study suggests that therapies targeting the pleasure and reward pathways of alcohol consumption might be more effective. By shifting treatment approaches away from solely addressing stress-responsive systems, experts hope to develop better interventions for individuals struggling with AUD and depression.

Understanding Alcohol’s Complex Effects

The study also calls into question the dominant theory that alcohol addiction stems from the brain’s attempt to maintain stability despite repeated heavy drinking. Researchers argue that a more nuanced understanding of alcohol’s impact on mental health is crucial for improving early intervention and treatment methods.

Participants with suicidal ideation or severe alcohol withdrawal symptoms were excluded from the study to ensure safety. As research continues, experts emphasize the importance of individualized approaches to treating AUD and co-occurring mental health conditions.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Individuals struggling with alcohol use or mental health concerns should seek guidance from a qualified healthcare professional.

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