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A recent study has shown promising results regarding the effects of intermittent fasting on postmenopausal women with rheumatoid arthritis. Conducted by Aryan Tavakoli and colleagues from the School of Nutritional Sciences and Dietetics at Tehran University of Medical Sciences, the research suggests that intermittent fasting may offer improvements in antioxidant levels, inflammatory markers, and liver function in women with rheumatoid arthritis, particularly those who are overweight or obese.
The randomized controlled trial involved 44 postmenopausal women with rheumatoid arthritis, who were divided into two groups: one following a 16:8 intermittent fasting regimen and the other maintaining their usual diet. The findings revealed that the intermittent fasting group experienced significant decreases in serum malondialdehyde levels and the neutrophil-to-lymphocyte ratio, which are both markers of inflammation. Additionally, this group showed increased catalase levels, an important antioxidant enzyme, as well as reductions in liver enzymes such as aspartate transaminase and alanine transaminase.
The researchers concluded that intermittent fasting could be a valuable nonpharmacological approach to managing rheumatoid arthritis in this specific population. The diet not only addressed the primary symptoms of the disease but also contributed to improvements in metabolic health.
However, while the results are promising, the authors emphasize that further research is needed to fully understand the underlying mechanisms and long-term effects of intermittent fasting. This study provides strong evidence for the potential of intermittent fasting as an adjunct therapy, especially for postmenopausal women with rheumatoid arthritis who are overweight or obese.
The full study can be accessed in Scientific Reports, DOI: 10.1038/s41598-025-86734-0.
Disclaimer: The findings of this study are based on the results of a randomized controlled trial and should not be interpreted as medical advice. It is recommended that individuals with rheumatoid arthritis or any other health conditions consult their healthcare providers before starting any new dietary regimen, including intermittent fasting.
