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Sydney, Australia – A groundbreaking study published Tuesday has revealed that a protein found in the blood of Australian oysters could offer a potent weapon in the fight against antibiotic-resistant superbugs.
Researchers at Southern Cross University (SCU) discovered that this unique protein possesses potent antibacterial properties, effectively killing bacteria such as Streptococcus pneumoniae (pneumonia) and Streptococcus pyogenes (strep throat). Furthermore, when combined with existing antibiotics, the oyster protein significantly amplified their effectiveness against Staphylococcus aureus and Pseudomonas aeruginosa, demonstrating a potency increase of 2 to 32 times.
The study, conducted in a laboratory setting, provides compelling evidence for the potential of natural oyster-derived products in combating bacterial infections. Importantly, the researchers confirmed that the protein is non-toxic to human cells, paving the way for potential development into a safe and effective antibiotic treatment.
The emergence of antimicrobial resistance (AMR) has become a critical global health concern. Superbugs, resistant to conventional antibiotics, pose a significant threat, increasing the risk of severe illness, disability, and mortality.
A key advantage of this oyster-derived protein lies in its ability to effectively target bacterial biofilms, complex communities of bacteria that shield themselves from antibiotics and the immune system. “The oyster hemolymph proteins were found to prevent biofilm formation and disrupt existing biofilms, making the bacteria more susceptible to antibiotic treatment even at lower doses,” explained co-author Kirsten Benkendorff from SCU’s Faculty of Science and Engineering.
This exciting discovery presents a unique opportunity for collaboration between researchers, the aquaculture industry, and the pharmaceutical sector to develop a novel antibiotic based on this promising natural compound.
Key takeaways:
- A protein found in Australian oyster blood exhibits potent antibacterial properties.
- It can kill bacteria directly and significantly enhance the effectiveness of existing antibiotics.
- The protein is non-toxic to human cells, making it a promising candidate for antibiotic development.
- It effectively targets bacterial biofilms, increasing the efficacy of antibiotic treatment.
- This research opens the door for collaboration to develop a new generation of antibiotics to combat the growing threat of superbugs.
