A groundbreaking device costing just pennies could be a game-changer for asthma patients worldwide, offering a simple and affordable solution to improve inhaler use and effectiveness. The device, called the Clip-Tone System, was born from a personal struggle and could transform asthma treatment for millions who struggle with correct inhaler technique.
The Clip-Tone System, developed by Professor Tariq Aslam from the University of Manchester, is a low-cost add-on to asthma inhalers. It uses a simple whistle device that clips onto the inhaler canister and emits an acoustic signal when the user inhales. This sound is then detected by a smartphone app developed by Clin-e-cal, a digital health company spun out of the university, which provides real-time feedback on inhaler technique.
A recent randomized controlled trial, the Clip-Tone System (CTS), involving 117 adult asthma patients, demonstrated significant improvements in inhaler technique over one, three, and six months. The results suggest that the system could play a crucial role in addressing a major issue in asthma care—poor inhaler usage. Up to 90% of inhaler users do not use their devices correctly, leading to reduced efficacy and ongoing symptoms.
The smartphone app, which offers day-to-day guidance, helps patients master proper inhalation techniques, such as inhalation time and coordination. The feedback provided by both acoustic signals and visual cues allows users to improve their technique, potentially leading to better asthma control and fewer side effects from medication.
The concept for the Clip-Tone System originated from Professor Aslam’s personal experience with his young son, Rafi, who suffered from asthma. Ten years ago, Professor Aslam created the original prototype—a system designed to help Rafi use his inhaler more effectively. The innovative device included a microphone in the inhaler’s mask that detected his inhalation, triggering a cartoon robot to respond with interactive storylines. This made the inhaler process less traumatic for Rafi and helped him learn how to use it correctly.
“I was determined to find a solution that would help my son master his inhaler technique without the stress and fear he had associated with it,” said Professor Aslam. “What started as a solution for Rafi ended up being a breakthrough for many others who struggle with inhalers.”
The new iteration of the system, which integrates the Clip-Tone whistle and the Clin-e-cal app, was further developed in collaboration with Professor Clare Murray, a specialist in pediatric respiratory medicine at the University of Manchester. The trial results showed that the Clip-Tone System significantly improved inhalation technique and duration, helping patients achieve a near-perfect score on a technique assessment. The improvement was sustained throughout the study period.
Professor Murray emphasized that proper inhaler technique is critical for effective asthma management. “Inhaler therapy is the mainstay of treatment for airway diseases, but up to 90% of users fail to use their inhalers correctly. Poor technique can lead to inadequate doses, causing ongoing symptoms and unnecessary stress for patients.”
The trial results suggest that the Clip-Tone System could be a valuable tool in training asthma patients, especially in the early stages of learning to use an inhaler, while also helping to maintain improved technique over time. As asthma care evolves, the system could play a pivotal role in reducing side effects and improving overall asthma control.
Although the Clip-Tone System is not yet available for sale, its inventors are optimistic that a partnership will emerge to bring this affordable and effective solution to the market, potentially transforming the lives of millions of asthma patients.