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Hyderabad, India — Researchers at BITS Pilani’s Hyderabad campus have developed an innovative device capable of detecting harmful bacteria, such as Pseudomonas aeruginosa, in just 15 minutes. This rapid diagnostic tool promises to revolutionize bacterial infection detection, particularly in resource-limited settings, and could significantly enhance healthcare delivery in hospitals and clinics.
The device, detailed in a study published in the IEEE Open Journal of Engineering in Medicine and Biology, utilizes a novel technique called Recombinase Polymerase Amplification (RPA). Unlike traditional bacterial detection methods that rely on slow processes and expensive laboratory equipment, this compact, affordable tool can quickly identify harmful bacteria on-site, allowing healthcare professionals to take timely action in treating infections.
According to Sanket Goel, Dean of Research & Innovation and co-lead researcher, this breakthrough has the potential to drastically reduce diagnostic turnaround times. “This device not only delivers results in just 15 minutes but is also designed to be easily used in resource-constrained environments where advanced laboratory facilities may not be available,” said Goel.
Pseudomonas aeruginosa, a bacterium known to cause severe infections like pneumonia and cystic fibrosis, is often challenging to detect promptly using conventional methods. However, the BITS Pilani device uses RPA, which operates at lower temperatures compared to traditional Polymerase Chain Reaction (PCR) methods, eliminating the need for costly thermal cycling equipment.
In addition to its speed and affordability, the device features a built-in photometric detection system capable of identifying trace amounts of bacterial DNA. This advanced technology enhances its sensitivity, ensuring more accurate results. The versatility of the platform also allows it to be adapted to detect other harmful bacteria, further expanding its potential use in healthcare settings.
Goel emphasized the transformative impact the device could have, particularly in areas with limited medical resources. “By enabling faster bacterial pathogen detection, we can improve patient outcomes by ensuring timely and appropriate treatment. This device has the potential to save lives and bring healthcare closer to those who need it most,” he said.
With its promise of faster diagnostics and cost-effectiveness, this device could become a game-changer in the battle against bacterial infections, offering new hope for healthcare providers worldwide.
