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As the global population ages rapidly, late-life depressive symptoms are becoming increasingly prevalent among older adults. These symptoms, which include feelings of sadness, lack of pleasure, and cognitive slowdowns, often come with additional issues such as loss of appetite, insomnia, poor concentration, and fatigue. Such symptoms are commonly linked to neurodegenerative changes in the brain associated with aging. Given the growing imperative to maintain the health of older adults, researchers have been exploring various preventative measures, including dietary factors.

A recent longitudinal study conducted by the Yong Loo Lin School of Medicine at the National University of Singapore (NUS Medicine) provides promising insights into how dietary habits during midlife may influence mental well-being in later years. This study, which followed 13,738 participants from the large-scale Singapore Chinese Health Study over approximately 20 years, suggests that higher fruit consumption in midlife is associated with a lower likelihood of depressive symptoms in later life.

The research team examined the consumption of 14 commonly eaten fruits in Singapore, including oranges, tangerines, bananas, papayas, watermelons, apples, and honey melons. The findings indicated that consuming a greater quantity of these fruits was linked to a reduced likelihood of experiencing depression later in life. The potential benefits are attributed to the high levels of antioxidants and anti-inflammatory micronutrients found in fruits, such as vitamin C, carotenoids, and flavonoids. These compounds are known to reduce oxidative stress and inhibit inflammatory processes that could contribute to depression.

Interestingly, the study did not find a similar association with vegetable consumption. This suggests that the protective effect against depressive symptoms may be more specific to fruits. The results, published in the Journal of Nutrition, Health and Aging, underscore the potential value of dietary interventions in mental health.

Professor Koh Woon Puay from the Healthy Longevity Translational Research Programme at NUS Medicine, who led the study, emphasized the importance of fruit consumption as a preventive strategy. “Our study highlights that individuals who consumed at least three servings of fruits a day were able to significantly reduce their likelihood of developing depression by at least 21% compared to those who had fewer than one serving a day,” Professor Koh said. He noted that incorporating one to two servings of fruit after each meal could be an effective strategy. The study also found no significant difference in results between high and low glycemic index fruits, making it easier for individuals with diabetes to choose fruits that fit their dietary needs without adversely affecting blood sugar levels.

Participants in the study were first assessed from 1993 to 1998, when they were around 51 years old, regarding their daily fruit and vegetable intake. In follow-up assessments from 2014 to 2016, when the participants were approximately 73 years old, depressive symptoms were measured using the Geriatric Depression Scale. Of the participants, 3,180 (23.1%) reported experiencing five or more depressive symptoms. After accounting for various factors such as medical history, smoking, physical activity, and sleep duration, the researchers found a clear association between higher fruit intake and lower odds of depressive symptoms.

Professor Koh highlighted the significance of these findings, noting that while previous studies have examined the relationship between diet and depression, many were conducted in Western populations and showed inconsistent results. This study is distinguished as the largest population-based investigation of its kind within an Asian context.

The implications of this research are considerable for public health initiatives. Promoting fruit consumption among individuals in mid-adulthood, typically between ages 40 and 65, could offer long-term mental health benefits as they age. Future research will continue to explore the impact of other modifiable behavioral factors, such as sleep duration and smoking, on mental health in older adults.

These findings provide a valuable perspective on the role of diet in mental health and suggest that simple dietary adjustments could play a significant role in improving quality of life for aging populations.

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